Lorazepam, which is a benzodiazepine drug. It is primarily prescribed for the short-term management of severe anxiety, certain types of seizures, and insomnia related to stress. Lorazepam works by increasing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that helps to calm nerve activity.
Key Information
- Typical Uses:
- Relief of anxiety symptoms or anxiety-associated depression.
- Short-term treatment of insomnia caused by anxiety.
- Sedation before surgical or dental procedures.
- Control of acute seizures (status epilepticus).
- Common Side Effects: Drowsiness, dizziness, fatigue, unsteadiness (ataxia), and muscle weakness.
- Safety Warnings:
- High Risk of Dependence: Lorazepam has a significant potential for dependence and addiction if used for extended periods.
- Withdrawal: Abruptly stopping this medication can lead to severe withdrawal symptoms, including seizures, tremors, and intense anxiety.
- Interactions: Combining Lorazepam with alcohol or opioids is dangerous and can result in severe respiratory depression or coma.
- Pregnancy/Nursing: It is generally not recommended during pregnancy or breastfeeding due to potential risks to the infant.
Usage
Lorazepam is typically taken as directed by a healthcare professional. For conditions like insomnia, a single dose is often prescribed at bedtime. The strength of the medication prescribed, such as 2mg, is determined by a physician based on the patient's specific needs and response to treatment.
For detailed clinical information, you can refer to the FDA-approved label via RxList or consult the Mayo Clinic guide on Lorazepam.

